SPM Active® is a revolutionary product by Metagenics. It contains 18-hydroxy-eicosapentaenoic acid (18-HEPE) and 17-hydroxy-docosahexaenoic acid (17-HDHA), which are metabolites, or products of the metabolism of EPA and DHA. To break this down even simpler, when you consume fish oil, which contains EPA and DHA, your body breaks it down into smaller components. Some of these components are 18-HEPE and 17-HDHA, which have very powerful anti-inflammatory and healing actions in the body.
SPM stands for “Specialized Pro-resolving Mediators”. SPMs are recently discovered cell signaling molecules that are derived from fish oil. What makes SPMs so valuable is that they are essentially much more active in performing beneficial effects in the body. Also, they are more easily turned into other very active chemicals (other types of SPMs) in the body.
The SPMs in SPM Active have been shown repeatedly in research studies to decrease inflammation, help fight off infection, aid in tissue regeneration and have even been used as a treatment for melanoma. It’s been used for cardiac tissue regeneration in mice after heart damage (think after a heart attack) and to quote one study “Our results indicate that 18-HEPE is a potential anticancer metabolite that mediates, at least in part, the preventive effect of n-3 PUFA on melanoma metastasis.” SPMs are one of the most exciting nutritional discoveries of recent times. Because uncontrolled inflammation is a key factor in many chronic diseases, a safe and natural product like SPM Active becomes of vital importance. SPM Active is like a new super-form of fish oil.
This product is non-GMO and gluten free. Storage: Keep tightly closed in a cool, dry place.
Calories (5), Calories from Fat (5), Total Fat (0.5g), Cholesterol, less than (5mg)
Active Fractionated Marine Lipid Concentrate* SPM content standardized to 18-hydroxy-eicosapentaenoic acid (18-HEPE) and 17-hydroxy-docosahexaenoic acid (17-HDHA) (500mg), Fractionated marine lipid concentrate [(anchovy and sardine oil, and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, water, pectin, and sorbitol), lemon oil.
|Ingredients||Amount Per Serving||% Daily Value|
|Serving Size||2 Softgels|
|Servings Per Container||60|
|Calories from Fat||10|
|Total Fat||1 g||2%*|
|Active Fractionated Marine Lipid Concentrate†||1 g||**|
|SPM content standardized to|
|18-hydroxy-eicosapentaenoic acid (18-HEPE) and|
|17-hydroxy-docosahexaenoic acid (17-HDHA)|
Recommended Dosage (adult)
Directions: Take two softgels once daily or as directed by your healthcare practitioner.
- Caution: If pregnant, nursing, or taking nutritional supplements or medications, consult your healthcare practitioner before use.
- Keep out of the reach of children.
- Do not use if safety seal is missing or broken.