Ceralin Forte by Metagenics is a specially-formulated supplement that offers neurological protection using a combination of vitamins, nutrients and herbs, including grape seed extract, L-5-MTHF (a bioactive form of folate), NAC, and acetyl-L-carnitine—which research suggests is able to cross the blood-brain barrier.
Acetyl-L-carnitine has been used in many clinical trials in Alzheimer’s disease patients with much success. In one double-blinded, placebo-controlled study performed over the course of one year, Alzheimer’s patients showed a significantly slower deterioration on 13 out of 14 measurements. The same outcome was seen in this study, with the authors giving the explanation that the acetyl-L-carnitine provided energy to maintain nerve cell membranes in the brain.
Also included in this formula is one of the best known sources of flavones– concentrated grape seed extract, which supports vascular (veins and arteries) and nerve health. The blood vessels are controlled by cells called endothelial cells. These cells control the constriction and relaxation of the blood vessels, which allow more or less blood to flow. Since blood flow is of primary importance to staying alive (stroke and heart attacks are simply lack of blood flow), keeping the vessels healthy and endothelial cells functioning optimally is on the top of the list of ways to stay healthy.
Poor endothelial function is associated with obesity, diabetes, smoking, high cholesterol and is predictive of atherosclerosis (blocking and hardening of the arteries leading to stroke and heart attacks). Optimal blood flow to the brain means a better functioning brain, and grape seed extract has been shown to increase blood flow, improve cholesterol and much more.
Also of note, in rat studies, grape seed extract has been able to directly improve the health of nerve cells by decreasing accumulated damage to the nerve cell (decreasing lipid peroxidation) and increasing antioxidant ability, which prevents free radicals from damaging the nerve cell.
N-acetly-L-cysteine, or NAC for short, has a long history of use in clinical settings for many reasons. It is the standard treatment for Tylenol overdose in the ER (as it aids the liver), it is the active ingredient in Mucomyst, a prescription medicine used to loosen and dissolve mucus in the lungs and now it is being researched as the first ever treatment to reverse the effects of traumatic brain injuries (TBI).
A study performed on 81 military personnel whom had experienced traumatic brain injuries in the line of duty were given NAC or placebo for 7 days. The results were those receiving NAC were significantly better than the placebo group and those receiving NAC within 24 hours of trauma had an 86% chance of complete symptom resolution vs 42% who had received placebo. So, the NAC more than doubled the chance of completely healing from a traumatic brain injury. The same effect has also been experienced in mice and rats repeatedly.
This product is gluten-free and non-GMO.
Thiamin (as thiamin mononitrate) (30mg), Riboflavin (30mg), Niacin (as niacinamide) (250mg), Vitamin B6 (as pyridoxine HCl) (25mg), Folate (as L-5-methyl tetrahydrofolate†) (500mcg), Vitamin B12 (as methylcobalamin) (500mcg), N-Acetylcysteine (600mg), Acetyl-L-Carnitine HCI (600mg), Grape Seed Extract (Vitis Vinifera)[standardized to 90% (180 mg) polyphenols] (204mg), Gelatin, microcrystalline cellulose, silica, magnesium stearate.
|Serving Size||3 Capsules|
|Servings Per Container||30|
|Thiamin (as thiamin mononitrate)||30 mg||2,500%|
|Niacin (as niacinamide)||250 mg||1,563%|
|Vitamin B6 (as pyridoxine HCl)||25 mg||1,471%|
|Folate (as calcium L-5-methyltetrahydrofolate†)||830 mcg DFE||208%|
|Vitamin B12 (as methylcobalamin)||500 mcg||20833%|
|Acetyl-L-Carnitine HCI||600 mg||*|
|Grape Seed Extract (Vitis vinifera) [standardized to 85% (170 mg) polyphenols]||204 mg||*|
Recommended Dosage (adult)
DIRECTIONS: Take three capsules daily or as directed by your healthcare practitioner.
- CAUTION: Do not use if pregnant or nursing.
- If you have a history of kidney stones or seizures, or are taking medication, consult your healthcare practitioner before use. Maintain adequate fluid intake while taking this product.
- Keep out of the reach of children